The Life Sciences Report: Joseph, your principal technology platform at Inovio is the DNA-based vaccine or immunotherapy. The traditional immunization platform involves giving a patient an attenuated virus, bacterium or antigen, and waiting a few weeks for a titer of antibodies to develop. What is the difference between the traditional immunization platform and Inovio's DNA immunization platform? Joseph Kim: Instead of using whole viruses, or weakened forms or parts of viruses, we use the DNA, or genetic blueprint, that encodes for the antigens (proteins) of our choice. We design all our products in the computer, using a genetic sequence database. We immunize patients with engineered DNA sequences that will turn into the antigens of choice in a natural process in the patient's own cells and body. TLSR: What are the advantages of synthesizing the antigens in the cells? JK: First, you can engineer the genetic sequences for the specific antigen.
Since the inception of the Investment Company Act of 1940, investors have grown to expect every mutual fund, closed-end fund (“CEF”), and exchange traded fund (“ETF”) to be treated as a “pass-through vehicle” for tax purposes. The entity itself would not pay any taxes, and all tax liabilities would be passed-through to the shareholders. That was the status quo for decades, until master limited partnership (“MLP”) funds came along.
UBS (UBS) rolled out the ETRACS Diversified High Income ETN (DVHI) on Thursday (9/19/13). The new exchange traded note (“ETN”) is targeted at investors desiring significant monthly income from a diversified multi-asset mix. It will track the new NYSE Diversified High Income Index minus the 0.84% annual tracking fee. The underlying index has a current yield of 7.7%, and the ETN will make monthly cash distributions.
[PR Newswire] - MIAMI, Oct. 30, 2014 /PRNewswire/ -- Gerry Cahill, president and CEO of Carnival Cruise Lines, announced today that he is retiring, effective November 30, after 20 years of service. Cahill, 63, has been CEO of Carnival Corporation's largest cruise brand since 2007, growing the cruise line to 24 ships – the largest in the company's fleet -- during his tenure. "Gerry has been instrumental in taking Carnival Cruise Lines to new heights as one of the preeminent brands in the cruise industry," said Arnold Donald, president and CEO of Carnival Corporation & plc, the world's largest cruise company.
Market Update: Comcast Corporation (NASDAQ:CMCSA) – Jordan’s Furniture Moves Into More Bandwidth and
Investors have had to endure much more volatility in the past few weeks. We may know why — the Federal Reserve put an expiration date on its $3 trillion-plus bond-buying program. But some investors don’t know how to proceed. The Fed’s easy-money policy — mainly known as quantitative easing, or QE — probably will end next year.
The Mining Report: What effect is the strong U.S. dollar having on base metal prices and base metal equities? Stefan Ioannou: Base metals are priced in U.S. dollars, so as the dollar rises in value, base metals fall in value. Right now, copper is testing the $3 per pound ($3/lb) level, and zinc is drifting down toward $1/lb.